|Dept:||Biochemistry/Biophysics & Molc Biol-LAS|
|Office:||3116 Molecular Bio|
The research projects in my group are focused on the study of protein folding, design and evolution using solution Nuclear Magnetic Resonance spectroscopy and a variety of complementary biophysical methods. How does a protein fold into it specific tridimensional structure and evolve to perform a given biological function remain key questions in most modern day diseases. Especially when combined with high-pressure perturbation, NMR spectroscopy offers the opportunity to characterize protein free-energy landscapes at an atomic resolution.
Related projects include the study of intrinsically disordered proteins, the characterization of amyloid-type peptides and the development of coarse-grained methods for protein folding simulations.
- Research interests
- Solution NMR of proteins
- B.S., Biology – University of Montpellier, France
M.S., Biophysics – University of Montpellier, France
Ph.D., Center for Structural Biology, Montpellier, France
Postdoctoral fellow, National Institutes of Health, NIDDK (Dr. Ad Bax), Bethesda, MD.