Department of Chemistry and Chemical Biology - Cornell University
Thursday, August 31, 2017
4:10 p.m. - 1414 Molecular Biology Building
Host: Stone Chen
“Zooming in on Spatial Control of Receptor Mediated Cellular Responses”
Cells respond to their physical environment and to chemical stimuli in terms of collective molecular interactions that are regulated in time and space. Small molecules may engage specific receptors to initiate a transmembrane signal, and the system amplifies this nanoscale interaction to microscale assemblies within the cell and often to longer length scales involving surrounding tissue and ultimately the whole organism. A striking example of signal integration over multiple length scales is the allergic immune response. IgE receptors (FcRI) on mast cells are the gatekeepers of this response, and this system has proven to be a valuable model for investigating receptor-mediated cellular activation. Our research spans the range of cellular responses.
BBMB GRADUATE STUDENTS ARE REQUIRED TO ATTEND!
PLEASE JOIN US AT 3:45 P.M. IN THE MBB ATRIUM FOR REFRESHMENTS
BBMB Seminar Schedule