Department of Biochemistry, Biophysics and Molecular Biology - Iowa State University
Thursday, March 2, 2017
4:10 p.m. - 1414 Molecular Biology Building
Host: Reuben Peters
“Gibberellin biosynthesis by symbiotic rhizobia”
Gibberellin (GA) phytohormones are incredibly important endogenous signaling compounds involved in plant growth and development, but are also produced by plant-associated fungi and bacteria, including rhizobia, the nitrogen-fixing, bacterial symbionts associated with legumes such as soybean and peas. Although convergent GA biosynthetic pathways in plants and fungi had been fully elucidated, production of GAs by bacteria was previously unresolved. Through characterization of a widely distributed bacterial biosynthetic gene cluster, we have been able to elucidate the GA biosynthetic pathway in rhizobia, showing that they produce either non-bioactive GA9, or a common bioactive form, GA4, depending on the bacterial species. Overall, this effort revealed that bacteria have evolved GA biosynthesis independently of plants and fungi, thus representing a third convergent pathway, and also provided insight into potential biochemical restraints underlying unique biosynthetic steps.
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PLEASE JOIN US AT 3:45 P.M. IN THE MBB ATRIUM FOR REFRESHMENTS